AZFL+ can only launch programs if the programs are installed to the folder(s) specified on the "Program List" window.  

Except for portable programs, AZFL+ searches for the selected program file within Program Files and if not found, it will search in Program Files (x86).  If not found in either folder, a message will be displayed that notifies the user that the program was not found.  In other words, the program being launched can only launch 
if installed to either Program Files or Program Files (x86).

Programs that are downloaded as a portable version, must be moved to "Program Files\AZFL+".  If these portable programs are not installed in that location, AZFL+ will not be able to launch them.

See the "Program List" window (available from the Main Console in AZFL+) for information on where to install programs.